It's a promising agent to treat Parkinson's disease because it blocks the CAv1.3 L-type calcium channel, which maintains a rhythmic pacemaking that the brain's dopamine neurons rely on to help coordinate movement.
But because the process is very energy demanding, it's believed to accelerate the degeneration of dopamine neurons that often trigger Parkinson's symptoms.
The three vintage-looking benches originally were built with oak slats, but they’re getting reassembled with Alaska yellow cedar, too.
It’s wood that Bunzey is recycling from the other benches.
But in terms of public use, the park benches are as accessible as a structure can get. “The timing was right, and the bench project was a perfect first project for Jim,” Cameron said in an email. The 139-year-old landmark is headquarters of the National Trust, and is part of the gateway from downtown Vancouver to the historic campus. Sixteen follow a modern design, featuring straight lines and right angles. Although they have a vintage look, reminiscent of a 1920s school desk, they likely were installed no more than 30 years ago, Cameron said.
“The visual impact can hardly be ignored since the benches look brand new.” Some of the bright yellow benches can be seen on or near the grounds of the O. Bunzey is replacing the wood in the 16 modern-looking designs with new pieces of Alaska yellow cedar.
Versatile in every form of theater craft, Robert Lepage is equally talented as a director, playwright, and actor with a creative and original approach that has shaken the dogma of classical stage direction to its foundations.